Pyogenic granuloma is an exuberant overgrowth of granulation tissue, frequently occurring in the oral cavity, most often involving the gingiva. It may also occur on the buccal mucosa, lip, tongue, or palate. It is a red to reddish-purple, soft, nodular mass that bleeds easily and grows rapidly, but is usually not painful. When it develops during pregnancy it is called pregnancy tumor or granuloma gravidarum. This 35-year-old pregnant woman presented with a large nodular vascular mass involved the floor of the mouth and lower gingiva of three months duration with the onset was at 12 weeks of gestation.