A 38-year-old married woman presented with an irregular, clear-cut, longitudinal crusted ulcer about 12×2.5 cm with pinkish red border involved the flexor aspect of the upper part of the forearm of 1 month duration. The ulcer seems to be self-induced with a caustic material (chemical burn) but the patient denied any history of self-mutilatin. The ulcer appearance plus the rapid evolution in addition to non-specific histological findings on skin biopsy may permit the diagnosis of dermatitis artefacta.
Flaccid bullae that rapidly rupture leaving raw erosions have been noticed since first one month of life. The blisters involved mainly the lower limbs specially acral parts but also the face and trunk were also affected. Fortunately, the nails and mucous membranes were spared. Skin biopsy showed skin split within the basal cells of the epidermis. Family history of similar condition was negative.
A two-day-old male neonate presented with a generalized erythroderma involved the entire body integument. He has been born enclosed in a collodion-like membrane. Ectropion and some degree of eclabium were evident on examination.
A 22-year-old male presented with a unilateral spotty brownish pigmentation on a background of lighter hyperpigmentation involved most of the left side of the face since birth.
Palmoplantar erythrodysesthesia syndrome isa relatively common syndrome induced by many chemotherapeutic agents, most frequently 5-fluouracil (5-FU),doxorubicin, and cytosine arabinoside. The reaction which is dose-dependent may occur in as many as 40% of treated patients.
The current case is a 62-year-old man with chronic lymphocytic leukemia who few days after starting chemotherapy complained of dysesthesia of the palms which in a few days followed by painful, symmetric dusky erythema and edema of the palms and less severe reaction on the dorsal surface of both hands.
A 5-year-old boy presented with pruritic red scaly patches on the side of the trunk of three months duration. The lesions had more active scaly borders. KOH examintion of the scales was positive for fungi. No history of contact with animals and no similar family history.
A solitary, circinate, red scaly plaque studded with pustules having well-defined border of one month duration. Excellent response to twice daily applications of combined topical Clotrimazole and Fusidic acid creams for 4 weeks.
A 75-year-old man presented with spontaneous idiopathic ecchymotic patches and one hemorrhagic blister on the dorsa of both hands of one week duration. The patient claimed no history of previous trauma or drug intake. Physical examination was negative and on investigations his blood profile was normal.
