All posts by Ahmed

Medical Student

INH-induced pellagra

History

          A very interesting case of pellagra localized to the exposed parts of the hands only. The patient was diagnosed as pulmonary tuberculosis and started anti-Tb therapy (Rifampicin+INH+ETB). Three months later she suffered well-circumscribed red scaly hyperpigmented rash on the back of both hands whereas other photosensitive areas were not affected. The rash had been diagnosed as eczematous and there was no response to topical corticosteroids for 6 weeks. On multivitamine supplemental therapy containing nicotinic acid 100 mg three times daily the rash improved dramatically within one week. The treating physician was asked to modify the anti-Tb therapy regarding INH which is the most probable cause of pellagroid rash.

Annular Urticaria

History

          A young adult man presented with a few days history of severely pruritic, evanescent geographical map-like wheals, some of which had an annular configuration involved most parts of the body but especially the trunk. There was no recognizable precipitating factor.

Morphea

History

        Morphoea is a localized form of scleroderma with hard, smooth, ivory-coloured, indurated, immobile plaques and give the appearance of hidebound skin but no internal sclerosis. There are many clinical variants of morphea (guttate, linear, localized, generalized, profunda and pansclerotic). Localized morphea is twice common in women as in men. It occurs in childhood as well as in adult life. The trunk is the most common site involved. Its prognosis is usually good, and the fibrosis slowly clears leaving slight depression and hyperpigmentation. The case depicted here  is a 20-year-old showed many resoluting plaques of morphea leaving slightly depressed hyperpigmented areas mainly on the trunk.

Squamous cell carcinoma

History

          A 65-year-old farmer presented with an ulcer on the lower lip that increased in size for one and a half year causing massive destruction of the lower lip. On examination one submental lymph node was palpable. Skin  biopsy showed SCC and lymph node was positive.

Polymorphous light eruption

Polymorphous light eruption2

History

         A middle-aged lady suffered pruritic, red, papular eruption confined to the sun-exposed parts of the face and neck of many months duration with exacerbations occur mainly after sun exposure. There was no history of topical agent appliaction or systemic drug intake  before the onset of the rash.