Category Archives: Connective Tissue Disorders

Connective tissue disorders

Dupuytren’s contracture

History

          A 68-year old man presented with idiopathic bilateral hard nodules involving the base of both ring fingers (usual site of Dupuytren’s contracture nodules) resulting in mild flexion deformity of both fourth fingers. On examination, hard cord-like flexor tendons within the palm extending from the bases of the ring fingers proximally to mid-palm.

Systemic lupus erythematosus

History

          A 12-year-old girl presented with fever, arthralgia and butterfly erythematous rash affected the face of two months duration. Her ESR was 60 mm/hr and the ANF and Anti-dsDNA antibody were positive.

En coup de sabre

History

         A 23-year-old female presented with a linear hyperpigmented depressed sclerotic plaque extending from the frontal hair line to the nasal root of more than 5 years duration. Other sites like the trunk and the extremities were not involved.

Morphea

History

        Morphoea is a localized form of scleroderma with hard, smooth, ivory-coloured, indurated, immobile plaques and give the appearance of hidebound skin but no internal sclerosis. There are many clinical variants of morphea (guttate, linear, localized, generalized, profunda and pansclerotic). Localized morphea is twice common in women as in men. It occurs in childhood as well as in adult life. The trunk is the most common site involved. Its prognosis is usually good, and the fibrosis slowly clears leaving slight depression and hyperpigmentation. The case depicted here  is a 20-year-old showed many resoluting plaques of morphea leaving slightly depressed hyperpigmented areas mainly on the trunk.

Morphea “en coup de sabre”

History

           A 5-year-old girl presented with a linear depressed tethered sclerosed plaque of one year duration. The plaque extended from the middle of the scalp across the forehead to the glabellar region. It has an ivory-white center and brownish borders.

Disseminated DLE

History

          A 47-year-old woman complained of an itchy rash on her back and forehead of 2 years duration. On examination multiple, well-demarcated, erythematous plaques with irregular hyperpigmented borders and hypopigmented and even depigmented scarred centers with some adherent scales and excoriations were found. ANF and Anti-dsDNA antibodies were negative.