A 47-year-old man presented with an asymptomatic, slowly growing, hard tumor with multinodular surface of fivee years duration on the arm. Biopsy was consistent with dermatofibrosarcoma protuberans.
A 63-year-old lady complained of > one-year history of persistent, moderately pruritic, unilateral, slightly infiltrative red plaque involved the left nipple and surrounding areolar region. The patient claimed partial improvement on topical steroid treatment which had been prescribed from time to time. O/E many left axillary lymph nodes were palpable. Skin biopsy confirmed the diagnosis of Paget’s disease of the breast and immunohistochemical assessment revealed positive CEA, EMA and negative S-100 protein. The patient had been referred to surgery.
A 23-year-old female presented with an asymptomatic, solitary, smooth-surfaced, pinkish firm nodule arose from the buccal surface of the cheeck of six months duration. It has been excized totally under local anesthesia with the biopsy finding was consistent with benign fibroma.
An 18-year-old male living in a rural area had long contact with domestic animals presented with a large, rounded, pinkish, oozing nodule with pus exuding from the orifices of hair follicles of more than one month duration on the side of the neck. It was associated with partial hair loss and retroauricular lymphadenopathy.
A 61-year-old man presented with a characteristic periorbital purplish discoloration (Heliotrope rash). It was associated with malar erythema and edema, less striking erythema of the neck and presternal area (Shawl sign) and atrophic papules over the knuckles of the fingers (Gottron’s papules). The skin signs had appeared simultaneously with muscle symptoms (weakness of proximal muscles). No underlying tumour was found. Investigations revealed: Negative ANA , Elevated CPK and abnormal EMG.
An 18-year-old male presented with widespread vitiligo associated with halo nevus on the chest (white halo surrounds a pigmented compound nevus of two years duration.
A 12-year-old boy presented with an asymptomatic skin-coloured to brownish dome-shaped firm nodule on the shin of six months duration. The patient denied any history of noticeable trauma to the lesional area prior to the appearance of the nodule.
A 45-year-old woman presented with a ten-day history of an erythematous plaques on both forearms and dorsa of the hands. The rash was pruritic, bilateral and symmetrical. Many lesions have target appearance. No previous drug intake or a preceding infection.