A two-day-old male neonate presented with a generalized erythroderma involved the entire body integument. He has been born enclosed in a collodion-like membrane. Ectropion and some degree of eclabium were evident on examination.
A 22-year-old male presented with a unilateral spotty brownish pigmentation on a background of lighter hyperpigmentation involved most of the left side of the face since birth.
A 75-year-old man presented with a small dark-red to brownish dome-shaped slightly crusted nodule developed within an irregularly-shaped congenital melanocytic nevus. The nodule has been noticed six months before presentation. It has been excised with a suitable safe margin and sent for histologic examination which revealed a nodular melanoma with malignant melanocytes reaching to mid dermis level.
Palmoplantar erythrodysesthesia syndrome isa relatively common syndrome induced by many chemotherapeutic agents, most frequently 5-fluouracil (5-FU),doxorubicin, and cytosine arabinoside. The reaction which is dose-dependent may occur in as many as 40% of treated patients.
The current case is a 62-year-old man with chronic lymphocytic leukemia who few days after starting chemotherapy complained of dysesthesia of the palms which in a few days followed by painful, symmetric dusky erythema and edema of the palms and less severe reaction on the dorsal surface of both hands.
A 5-year-old boy presented with pruritic red scaly patches on the side of the trunk of three months duration. The lesions had more active scaly borders. KOH examintion of the scales was positive for fungi. No history of contact with animals and no similar family history.
A solitary, circinate, red scaly plaque studded with pustules having well-defined border of one month duration. Excellent response to twice daily applications of combined topical Clotrimazole and Fusidic acid creams for 4 weeks.
A 75-year-old man presented with spontaneous idiopathic ecchymotic patches and one hemorrhagic blister on the dorsa of both hands of one week duration. The patient claimed no history of previous trauma or drug intake. Physical examination was negative and on investigations his blood profile was normal.
This 36-year-old man gave history of multiple wart-like lesions on one side of the abdomen since early childhood. On examination, a zosteriform verrucous epidermal nevus was found. The nevus consisted of numerous, brownish plane wart- like papules of unilateral distribution involving mainly T10 dermatome of the right side of the abdomen. The lesions were asymptomatic and there were no associated neurological or skeletal abnormalities.